Jason Buenrostro, PhD, is a cellular and molecular biologist focused on understanding the mechanisms that regulate gene expression. He has pioneered several technologies that provide deeper insights into how and when genes are expressed. Among these technologies, Buenrostro developed ATAC-seq and single-cell ATAC-seq, methods that identify regions of chromatin accessibility in rare cell types or across single-cells. These technologies are now broadly deployed enabling advances in understanding cellular diversity and function. Buenrostro's recent innovations, include multi-omic and spatial genomic methods that allow for the simultaneous study of chromatin accessibility, gene expression, and spatial context within tissues, providing a comprehensive view of cellular function and its impact on health and disease.

Buenrostro received his PhD in Genetics from Stanford University under the mentorship of William Greenleaf, PhD, and Howard Chang, MD, PhD. He completed an early independence fellowship as a Junior Fellow at the Harvard Society of Fellows and a Broad Institute Fellow. Currently, Buenrostro is an Associate Professor in the Department of Stem Cell and Regenerative Biology at Harvard University and an Institute Member of the Broad Institute. His work has earned numerous accolades, including the NIH Director’s New Innovator Award, the Allen Distinguished Investigator Award, and being named one of MIT Technology Review's "35 Innovators Under 35."